Comparison of average size of introns, exons, and intergenic regions within avian, reptilian, and mammalian genomes

Range Table - link
Organism Vertebrates
Reference Zhang G et al., Comparative genomics reveals insights into avian genome evolution and adaptation. Science. 2014 Dec 12 346(6215):1311-20. doi: 10.1126/science.1251385 p.1314 figure 2APubMed ID25504712
Method Abstract: "[Investigators] explored bird macroevolution using full genomes from 48 avian species representing all major extant clades."
Comments P.1312 left column bottom paragraph: "[Investigators] compared the average size of genomic elements of birds with 24 mammalian and the three nonavian reptile genomes. Avian protein-coding genes were on average 50 and 27% shorter than the mammalian and reptilian genes, respectively (Fig. 2A). This reduction is largely due to the shortening of introns and reduced intergenic distances that resulted in an increased gene density (Fig. 2A). Such genomic contraction has also evolved convergently in bats (fig. S11), the only flying mammalian group. The condensed genomes may represent an adaptation tied to rapid gene regulation required during powered flight (refs 34, 35)."
Entered by Uri M
ID 117105