Range |
normally several hundred: upon nutrient starvation <50 lysosomes/cell
|
Organism |
Mammals |
Reference |
Haoxing Xu and Dejian Ren, Lysosomal Physiology, Annu. Rev. Physiol. 2015. 77: 57–80 doi: 10.1146/annurev-physiol-021014-071649 p.58 3rd paragraph |
Primary Source |
[7] Yu L et al., Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature. 2010 Jun 17465(7300):942-6. doi: 10.1038/nature09076 [14] Bandyopadhyay D et al., Lysosome transport as a function of lysosome diameter. PLoS One. 2014 Jan 31 9(1):e86847. doi: 10.1371/journal.pone.0086847PubMed ID20526321, 24497985
|
Comments |
P.58 3rd paragraph: "There are normally several hundred lysosomes in each mammalian cell. Upon nutrient starvation, lysosomal number is dramatically reduced to <50 per cell, and the size of the lysosome is increased to 500–1,500 nm as a result of membrane fusion (primary sources)." |
Entered by |
Uri M |
ID |
117094 |