Number of lysosomes in each mammalian cell

Range normally several hundred: upon nutrient starvation <50 lysosomes/cell
Organism Mammals
Reference Haoxing Xu and Dejian Ren, Lysosomal Physiology, Annu. Rev. Physiol. 2015. 77: 57–80 doi: 10.1146/annurev-physiol-021014-071649 p.58 3rd paragraph
Primary Source [7] Yu L et al., Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature. 2010 Jun 17465(7300):942-6. doi: 10.1038/nature09076 [14] Bandyopadhyay D et al., Lysosome transport as a function of lysosome diameter. PLoS One. 2014 Jan 31 9(1):e86847. doi: 10.1371/journal.pone.0086847PubMed ID20526321, 24497985
Comments P.58 3rd paragraph: "There are normally several hundred lysosomes in each mammalian cell. Upon nutrient starvation, lysosomal number is dramatically reduced to <50 per cell, and the size of the lysosome is increased to 500–1,500 nm as a result of membrane fusion (primary sources)."
Entered by Uri M
ID 117094