Usual affinity between immunoglobulins and their specific antigens

Range 10^4 - 10^7 mol/liter
Organism Unspecified
Reference Saji F, Samejima Y, Kamiura S, Koyama M. Dynamics of immunoglobulins at the feto-maternal interface. Rev Reprod. 1999 May4(2):81-9 p.85 left column top paragraphPubMed ID10357095
Comments P.84 right column bottom paragraph: "As monoclonal antibodies raised against the myeloid FcγRs, FcγRI, FcγRII, FcγRIII, have become available, a number of immunohistochemical studies have been performed on the placenta. The results of these studies on human term placenta are summarized (Table 2, Fig. 2). In these studies, careful evaluation of control staining has been done, because the affinity between immunoglobulins and their specific antigens is usually 10^4–10^7 mol/l, which is equivalent to the affinity of placental FcγRs for IgG."
Entered by Uri M
ID 117059