Ratio between endothelial cell/pericyte

Range in CNS microvasculatures 1:1-3:1: in muscle 100:1 endothelial cell:pericyte
Organism Unspecified
Reference Daneman R, Prat A. The blood-brain barrier. Cold Spring Harb Perspect Biol. 2015 Jan 5 7(1):a020412. doi: 10.1101/cshperspect.a020412 p.4 left column bottom paragraphPubMed ID25561720
Primary Source Shepro D, Morel NM. Pericyte physiology. FASEB J. 1993 Aug7(11):1031-8 DOI: 10.1096/fasebj.7.11.8370472PubMed ID8370472
Comments P.4 left column bottom paragraph: "CNS [central nervous system] PCs [Pericytes] have been shown to have unique properties compared to PCs in other tissues. CNS PCs are derived from the neural crest, in contrast with PCs in many peripheral tissues, which are derived from the mesoderm (Majesky 2007). In addition, CNS microvasculatures have the highest CNS PCs coverage of any tissue, with an endothelial:pericyte ratio estimated between 1:1 and 3:1, whereas the muscle has a ratio of 100:1 (primary source)."
Entered by Uri M
ID 117040