Viral concentration in gut

Range ≤10^8 viral particles/gram feces
Organism Human Homo sapiens
Reference Fortier LC, Sekulovic O. Importance of prophages to evolution and virulence of bacterial pathogens. Virulence. 2013 Jul 1 4(5):354-65. doi: 10.4161/viru.24498 p.354 left column bottom paragraphPubMed ID23611873
Primary Source [4] Breitbart M et al., Viral diversity and dynamics in an infant gut. Res Microbiol. 2008 Jun159(5):367-73. doi: 10.1016/j.resmic.2008.04.006 [5] Breitbart M et al., Metagenomic analyses of an uncultured viral community from human feces. J Bacteriol. 2003 Oct185(20):6220-3 DOI: 10.1128/jb.185.20.6220-6223.2003PubMed ID18541415, 14526037
Method Primary source [4] abstract: "Metagenomic sequencing of DNA viruses from the feces of a healthy week-old infant revealed a viral community with extremely low diversity…Certain sequences were stable in the infant's gut over the first 3 months of life, but microarray experiments demonstrated that the overall viral community composition changed dramatically between 1 and 2 weeks of age." Primary source [5] abstract: "Here [investigators] present the first metagenomic analyses of an uncultured viral community from human feces, using partial shotgun sequencing."
Comments P.354 left column bottom paragraph: "The human gut can contain up to 10^8 viral particles per gram of feces and most of these viruses are bacteriophages (primary sources)."
Entered by Uri M
ID 117013