| Range |
prokaryotes 23%: non-animal eukaryotes (protists, fungi, and plants) 29%: nonchordate animals 27 %
|
| Organism |
Mouse Mus musculus |
| Reference |
Gerhart J, Kirschner M. The theory of facilitated variation. Proc Natl Acad Sci U S A. 2007 May 15 104 Suppl 1: 8582-9 DOI: 10.1073/pnas.0701035104 p.8584 left column 3rd paragraphPubMed ID17494755
|
| Primary Source |
[8] Mouse Genome Sequencing Consortium, Waterston RH et al., Initial sequencing and comparative analysis of the mouse genome. Nature. 2002 Dec 5 420(6915):520-62 DOI: 10.1038/nature01262PubMed ID12466850
|
| Method |
Primary source abstract: "Here, [investigators] report the results of an international collaboration to produce a high-quality draft sequence of the mouse genome. [They] also present an initial comparative analysis of the mouse and human genomes, describing some of the insights that can be gleaned from the two sequences." |
| Comments |
P.8584 left column 3rd paragraph: "Recent genome analysis has brought quantification to the impressions about conservation. More than 80 metazoan genomes have now been sequenced, and a typical case is the mouse (primary source). Of its total set of gene sequences, 23% are shared with prokaryotes, a further 29% are shared with non-animal eukaryotes (protists, fungi, and plants), and a further 27% are shared with nonchordate animals. Thus, 79% of mouse genes retain pre-Cambrian sequences. Reciprocally stated, only 21% of its functional components are unique to chordates, much less vertebrates, mammals, or mice." |
| Entered by |
Uri M |
| ID |
117010 |