Fraction of genome constituted of highly divergent prophage remnants

Value 22 %
Organism Archaea Halobacterium sp. NRC-1
Reference Ramisetty BCM, Sudhakari PA. Bacterial 'Grounded' Prophages: Hotspots for Genetic Renovation and Innovation. Front Genet. 2019 Feb 12 10: 65. doi: 10.3389/fgene.2019.00065 p.4 left column top paragraphPubMed ID30809245
Primary Source Bonneau, R., Baliga, N. S., Deutsch, E. W., Shannon, P., and Hood, L. (2004). Comprehensive de novo structure prediction in a systems-biology context for the archaea Halobacterium sp. NRC-1. Genome Biol. 5:R52. doi: 10.1186/gb-2004-5-8-r52PubMed ID15287974
Method Primary source abstract: "Simultaneous analysis of the association network, coordinated mRNA level changes in microarray experiments and genome-wide structure prediction has allowed [investigators] to glean significant biological insights into the roles of several Halobacterium NRC-1 proteins of previously unknown function, and significantly reduce the number of proteins encoded in the genome of this haloarchaeon for which no annotation is available."
Comments P.4 left column top paragraph: "A large number of IS (insertion sequences) elements that are collectively referred to as minichromosomes comprise highly divergent prophage remnants constituting 22% of Halobacterium sp. NRC-1 genome, and code for transposases associated with phage genomes and other mobile genetic elements (primary source)."
Entered by Uri M
ID 116993