Number of residues in conserved POU-specific domain (of the POU class of transcription factors)

Range ~70 amino acids
Organism Unspecified
Reference Bürglin TR, Affolter M. Homeodomain proteins: an update. Chromosoma. 2016 Jun125(3):497-521. doi: 10.1007/s00412-015-0543-8 p.511 right column top paragraphPubMed ID26464018
Primary Source Herr W et al., The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev. 1988 Dec2(12A):1513-6 DOI: 10.1101/gad.2.12a.1513PubMed ID3215510
Comments P.511 right column top paragraph: "The POU class of transcription factors is characterized by a conserved POU-specific domain of about 70 resides that is located upstream of a HD (homeodomain) that usually contains a serine residue at position 50 of the HD (homeodomain)(primary source) (Table 1)."
Entered by Uri M
ID 116973