Fraction of all transcription factors that are homeodomain (HD) proteins

Range ~15% - 30 % of all transcription factors
Organism Metazoa animals
Reference Bürglin TR, Affolter M. Homeodomain proteins: an update. Chromosoma. 2016 Jun125(3):497-521. doi: 10.1007/s00412-015-0543-8 p.498 left column 3rd paragraphPubMed ID26464018
Primary Source de Mendoza A et al., Transcription factor evolution in eukaryotes and the assembly of the regulatory toolkit in multicellular lineages. Proc Natl Acad Sci U S A. 2013 Dec 10 110(50):E4858-66. doi: 10.1073/pnas.1311818110PubMed ID24277850
Comments P.498 left column 3rd paragraph: "Overall, about 15–30 % of all transcription factors in animals are HD proteins (primary source), which represents about 0.5–1.25 % of all proteins in a given species."
Entered by Uri M
ID 116967