Length of disordered regions in many metal-binding proteins

Range ~30-50 residues (amino acids)
Organism Rat Rattus norvegicus
Reference Theillet FX et al., Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs). Chem Rev. 2014 Jul 9 114(13):6661-714. doi: 10.1021/cr400695p p.6663 right column bottom paragraphPubMed ID24901537
Primary Source [57] Lobley GE, Bremner DM, Holtrop G, Johnstone AM, Maloney C. Impact of high-protein diets with either moderate or low carbohydrate on weight loss, body composition, blood pressure and glucose tolerance in rats. Br J Nutr. 2007 Jun97(6):1099-108 DOI: 10.1017/S0007114507691934PubMed ID17397561
Comments P.6663 right column bottom paragraph: "In addition, many metal-binding proteins contain extended disordered regions (∼30–50 residues) (primary source) and metal binding can affect their mean net charge to a degree that they become ordered."
Entered by Uri M
ID 115800