Fraction of genes that are essential metabolic genes

Range Mycoplasma pneumoniae 56.6%: Escherichia coli 19% %
Organism bacteria
Reference Wodke JA et al., Dissecting the energy metabolism in Mycoplasma pneumoniae through genome-scale metabolic modeling. Mol Syst Biol. 2013 9: 653. doi: 10.1038/msb.2013.6 p.14 right column 4th paragraphPubMed ID23549481
Primary Source Baba T et al., Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol. 2006 2: 2006.0008. DOI: 10.1038/msb4100050 AND Joyce AR et al., Experimental and computational assessment of conditionally essential genes in Escherichia coli. J Bacteriol. 2006 Dec188(23):8259-71 DOI: 10.1128/JB.00740-06PubMed ID16738554, 17012394
Comments P.14 right column 4th paragraph: "M. pneumoniae has an exceptionally high percentage of essential metabolic genes (56.6% versus. 19% in E. coli, primary sources) for which consequently no other gene can buffer the loss of function caused from gene deletion."
Entered by Uri M
ID 115504