Estimated fraction of mitochondrial inner membrane that is "packed" with proteins within the membrane

Range ~40 % of inside of mitochondrial inner membrane
Organism Rat Rattus norvegicus
Reference Szenk M, Dill KA, de Graff AMR. Why Do Fast-Growing Bacteria Enter Overflow Metabolism? Testing the Membrane Real Estate Hypothesis. Cell Syst. 2017 Aug 235(2):95-104. doi: 10.1016/j.cels.2017.06.005. p.100 right column top paragraphPubMed ID28755958
Primary Source Schwerzmann K, Cruz-Orive LM, Eggman R, Sänger A, Weibel ER. Molecular architecture of the inner membrane of mitochondria from rat liver: a combined biochemical and stereological study. J Cell Biol. 1986 Jan102(1):97-103.PubMed ID2867101
Method Primary source title: "a combined biochemical and stereological study."
Comments P.100 right column bottom top paragraph: "This bulbous nature of membrane proteins could also resolve why the mitochondrial inner membrane, among the most densely packed ever recorded, is estimated to be ‘‘only’’ around 40% protein within the membrane (primary source)."
Entered by Uri M
ID 114712