| Range |
~1.8E10 ATPs/femtoliter of cell volume
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Szenk M, Dill KA, de Graff AMR. Why Do Fast-Growing Bacteria Enter Overflow Metabolism? Testing the Membrane Real Estate Hypothesis. Cell Syst. 2017 Aug 235(2):95-104. doi: 10.1016/j.cels.2017.06.005. p.98 left column top paragraphPubMed ID28755958
|
| Primary Source |
Stouthamer AH, Bettenhaussen CW. A continuous culture study of an ATPase-negative mutant of Escherichia coli. Arch Microbiol. 1977 Jun 20 113(3):185-9 AND Hempfling WP, Mainzer SE. Effects of varying the carbon source limiting growth on yield and maintenance characteristics of Escherichia coli in continuous culture. J Bacteriol. 1975 Sep123(3):1076-87 AND Feist AM et al., A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information. Mol Syst Biol. 2007 3: 121 DOI: 10.1038/msb4100155PubMed ID141918, 169226, 17593909
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| Comments |
P.98 left column top paragraph: "Above, [investigators] reasoned about the effect of S [surface area] and V [volume] on the rate of glucose uptake, that is, the raw material for the cell’s energy supply. They are also intimately related to the cell’s rate of ATP demand. But how large is this demand and how much membrane space is needed to supply it? [They] define R[ATP]-demand as the number of ATP molecules per unit time, per unit cell volume, that must be produced in order for a cell to sustain a growth rate λ. The amount of ATP, αB, needed to produce E. coli biomass aerobically on glucose is roughly 18 billion ATP molecules per femtoliter of cell volume (primary sources) (Table S1A)." See BNID 101983 |
| Entered by |
Uri M |
| ID |
114702 |