Peptide bond hydrolyses parameters

Range Table - link
Organism Generic
Reference R. Bruce Martin, Free energies and equilibria of peptide bond hydrolysis and formation, Biopoly 45: 351–353, 1998 DOI: 10.1002/(SICI)1097-0282(19980415)45:5<351::AID-BIP3>3.0.CO2-K p.352 table I
Method Abstract: "With a minimum of assumptions, this paper deduces the free energies of hydrolysis of a variety of peptide bonds."
Comments P.352 right column bottom paragraph: "For the peptides in Table I there are but two experimental values for the overall free energy change: ΔGh, -3.6 kcal/mole for glycylglycine hydrolysis [ref 5], and -0.4 kcal/mole for N-benzoyltyrosine–glycinamide hydrolysis [ref 4]. These entries appear at the top and bottom of the last column in Table I. For these two peptides Eq. (1) yields for ΔGm [the free energy of hydrolysis of the amide bond to uncharged products] values of 6.3 and 5.3 kcal/mole at the top and bottom of the fourth column of Table I." See notes beneath table
Entered by Uri M
ID 114386