---

Fraction of infections that result in moderate to severe disease

Range	~20 %
Organism	Lassa virus
Reference	Prescott JB et al., Immunobiology of Ebola and Lassa virus infections. Nat Rev Immunol. 2017 Mar17(3):195-207. doi: 10.1038/nri.2016.138 p.196 right column 3rd paragraphPubMed ID28111475
Primary Source	[8] Ogbu, O., Ajuluchukwu, E. & Uneke, C. J. Lassa fever in West African sub-region: an overview. J. Vector Borne Dis. 44, 1–11 (2007) [23] Gunther, S. & Lenz, O. Lassa virus. Crit. Rev. Clin. Lab. Sci. 41, 339–390 (2004) DOI: 10.1080/10408360490497456PubMed ID17378212, 15487592
Comments	P.196 right column 3rd paragraph: "The majority of LASV [Lassa virus] infections are asymptomatic or mild in nature [refs 20, 21, 22]. It is generally thought that approximately 20% of infections result in moderate to severe disease, which can be associated with haemorrhagic manifestations and multi-organ failure [primary sources]."
Entered by	Uri M
ID	114194