Radii of nucleolus, nucleoplasm, cytoplasm and average nucleus (taken as spheres)

Range nucleolus 0.9: nucleoplasm 2.7: cytoplasm 5.8: average nucleus 2.5 μm
Organism Eukaryotes
Reference Heyden & Oritz, Investigation of the influence of viscoelasticity on oncotripsy, Computer Methods in Applied Mechanics and Engineering, Volume 314, 1 February 2017, Pages 314-322, link p.316 top paragraph
Primary Source [16] H. Lodish et al. Molecular Cell Biology (fifth ed.), WH Freeman, New York (2004) [18] G.M. Cooper The Cell: A Molecular Approach (second ed.), Sinauer Associates, Sunderland, MA, USA (2000) [19] P.H. Guttman, S. Halpern Nuclear-nucleolar volume ratio in cancer Am. J. Cancer, 25 (1935), pp. 802-806 link
Comments P.315 bottom paragraph: "The geometric model of the cells presented in this study takes into account the cytoplasm, nucleus and nucleolus, as well as the plasma membrane and nuclear envelope, Fig. 4. Each of the cell constituents is idealized to be of spheroidal shape, whereby the nucleolus, nucleoplasm and cytoplasm are defined as spheres with radii 0.9 μm, 2.7 μm and 5.8 μm, respectively, and subsequently scaled by a factor of 1.2 in two dimensions. Measurements are based on an average nuclear diameter of 5 μm as reported in [primary source 18] and nucleus-to-cell as well as nucleus-to-nucleolus ratios as presented in [primary sources 19,16]."
Entered by Uri M
ID 113849