Duration of embryonic myoblast fusions

Value 5.5 hours
Organism Fruit fly Drosophila melanogaster
Reference Shinn-Thomas JH, Mohler WA. New insights into the mechanisms and roles of cell-cell fusion. Int Rev Cell Mol Biol. 2011 289 :149-209. doi: 10.1016/B978-0-12-386039-2.00005-5 p.162 3rd paragraphPubMed ID21749901
Primary Source M. Bate, The embryonic development of larval muscles in Drosophila, Development (Cambridge, England), 110 (1990), pp. 791–804PubMed ID2100994
Comments P.162 3rd paragraph: "Drosophila embryo myogenesis has been the muscle biology system that has given the most comprehensive working model for myoblast fusion during muscle development. Drosophila myogenesis proceeds mostly during embryogenesis—although some myoblast fusions do occur during pupal development—making the Drosophila embryo a convenient platform for the study of cell–cell fusion (Rochlin et al., 2010). Embryonic myoblast fusions occur over a 5.5-h time period and produce muscles whose size is proportional to the number of myoblast fusions (2–24 nuclei per muscle) (primary source)."
Entered by Uri M
ID 113609