| Range |
in rats and in haematologically normal man 4-7days: in patients with Hodgkin's disease 2.5-5.5days days
|
| Organism |
Mammals |
| Reference |
Schick P, et al., Autotransfusion of 3H-cytidine-labelled blood lymphocytes in patients with Hodgkin's disease and non-Hodgkin patients. II. Exchangeable lymphocyte pools. Acta Haematol. 1975 53(4):206-18. p.214PubMed ID808930
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| Primary Source |
[4] Caffrey RW, Rieke WO, Everett NB. Radioautographic studies of small lymphocytes in the thoracic duct of the rat. Acta Haematol. 1962 28: 145-54. [21] Schick P et al., Kinetics of lymphocytes in Hodgkin's disease. Blut. 1973 Oct27(4):223-35.PubMed ID13875511, 4744339
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| Method |
Abstract: "The dilution in the circulating blood of lymphocytes lablled in vitro with 3H-cytidine was examined after autotransfusion in 9 patients with Hodgkin's disease (HD) stage II A-IV B, 5 of whom were untreated in 2 untreated patients with carcinoma, and in 1 treated patient with scleroderma." |
| Comments |
P.213 bottom paragraph: "The mean life span of short-lived small blood lymphocytes was reported to be 4-7 days in rats and haematologically normal man [primary source 4, unpublished data] and 2.5-5.5 days in patients with Hodgkin’s disease [primary source 21]." |
| Entered by |
Uri M |
| ID |
113433 |