Blood transit time of exchangeable lymphocytes

Range patients with Hodgkin's disease 37±18: other patients 26±6 min
Organism Human Homo sapiens
Reference Schick P, et al., Autotransfusion of 3H-cytidine-labelled blood lymphocytes in patients with Hodgkin's disease and non-Hodgkin patients. II. Exchangeable lymphocyte pools. Acta Haematol. 1975 53(4):206-18. Abstract & p.213 2nd paragraphPubMed ID808930
Method Abstract: "The dilution in the circulating blood of lymphocytes lablled in vitro with 3H-cytidine was examined after autotransfusion in 9 patients with Hodgkin's disease (HD) stage II A-IV B, 5 of whom were untreated in 2 untreated patients with carcinoma, and in 1 treated patient with scleroderma."
Comments Abstract: "The blood transit time of exchangeable lymphocytes was 37±18 min in the patients with HD and 26±6 min in the other patients." P.213 2nd paragraph: "The transit times calculated in [investigators’] patients are on an average 37.5±18min in cases C-L and 26±6min in cases M, N and S. Since these values agree with the blood transit times mentioned above, it is concluded that the random loss of labelled small lymphocytes after autotransfusion reflects the emigration of recirculating cells from the intravascular pool into the extravascular part of the recirculating pool."
Entered by Uri M
ID 113431