Daily turnover of cells

Range in the skin 7E8: in the mucosa of the gastrointestinal tract 56E9 cells/day
Organism Human Homo sapiens
Reference Fliedner TM, Graessle DH. Hematopoietic cell renewal systems: mechanisms of coping and failing after chronic exposure to ionizing radiation. Radiat Environ Biophys. 2008 Feb47(1):63-9. DOI: 10.1007/s00411-007-0148-6 p.64 left column top paragraphPubMed ID18087709
Primary Source [2] Fliedner TM, Steinbach KH, Hoelzer D (1976) Adaptation of environmental changes: the role of cell-renewal systems. In: Finck ES (ed) The effects of enviornment on cells and tissues. Excerpta Medica, Amsterdam, pp 20–38
Comments P.63 right column bottom paragraph: "The extent of the daily cellular renewal is of an amazing magnitude. The investigation of the physiology and pathophysiology of cellular renewal was made possible by the extensive use of radionuclides, notably of tritiated thymidine (3HTdR), but also of DF32P, 59Fe, 51Cr or 35S. These studies lead to the conclusion that the daily turnover in the actively renewing cell system amounts to 490×10^9 cells in the hematopoietic renewal system [BNID 113413], 0.7×10^9 cells in the skin and 56×10^9 cells in the mucosa of the gastrointestinal tract [primary source]. "
Entered by Uri M
ID 113419