Comments |
P.377 right column bottom paragraph: "In eukaryotic cells, it is classically admitted that phosphatidylinositol (PtdIns), phosphatidylinositol 4-monophosphate (PtdIns(4)P) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) are kept in a steady-state level in the inner leaflet of the plasma membrane, because of continuous sequential phosphorylation/dephosphorylation reactions by specific kinases and phosphatases, which are not yet fully identified [ref 2], [ref 5]. This so-called “futile cycle” accounts for about 7% of the basal ATP consumption in human blood platelets [primary source]." |