| Comments |
P.4 left column bottom paragraph: "As compared with the association and dissociation phases of sensorgrams of the fractionated CS [Chondroitin sulfate] from bovine tracheal cartilage with L-selectin, those of CS from whale cartilage were steeper, that is, the interaction with CS from whale cartilage with L-selectin is tighter. Kinetic parameters such as association constant (KA), dissociation constant (KD), association rate constant (Ka), and dissociation rate constant (Kd) were calculated as the Langmuir formula. Evaluation of the kinetic parameters (Table 3) indicated that (KD) of the fractionated CS with 21 kDa in both CS was the smallest and there was the tendency of (KD) to increase in a molecular weight-dependent manner." |