Kinetic parameters for the interaction of fractionated chondroitin sulfate with immobilized L-selectin

Range Table - link kDa
Organism Mammals
Reference Naoko Igarashi et al., Effect of Molecular Sizes of Chondroitin Sulfate on Interaction with L-Selectin, International Journal of Carbohydrate Chemistry, Volume 2013 (2013), Article ID 856142, 9 pages link p.5 table 3
Comments P.4 left column bottom paragraph: "As compared with the association and dissociation phases of sensorgrams of the fractionated CS [Chondroitin sulfate] from bovine tracheal cartilage with L-selectin, those of CS from whale cartilage were steeper, that is, the interaction with CS from whale cartilage with L-selectin is tighter. Kinetic parameters such as association constant (KA), dissociation constant (KD), association rate constant (Ka), and dissociation rate constant (Kd) were calculated as the Langmuir formula. Evaluation of the kinetic parameters (Table 3) indicated that (KD) of the fractionated CS with 21 kDa in both CS was the smallest and there was the tendency of (KD) to increase in a molecular weight-dependent manner."
Entered by Uri M
ID 113388