Daily turnover of endothelial cells in lung

Range ~1 % of total number of cells
Organism Unspecified
Reference Bowden DH. Cell turnover in the lung. Am Rev Respir Dis. 1983 Aug128(2 Pt 2):S46-8. DOI: 10.1164/arrd.1983.128.2P2.S46 p.S47 right column 2nd paragraphPubMed ID6881708
Primary Source 18) Crystal RG. The cell population of the normal lung. In: Bouhuys A, ed, Lung cells in disease. Amsterdam: Elsevier/North-Holland Biomedical Press, 1976:17-38
Comments P.S47 right column 2nd paragraph: "Endothelial cells are the most numerous of pulmonary cells, accounting for some 40% of the total (BNID 113055). They represent a constantly renewed population with a daily turnover rate of about 1% of their total number (primary source). This figure, an average value for all vessels in the lung, takes no account of varying rates of mitotic activity in different parts of the vascular tree (ref 19). In the systemic circulation, endothelial mitoses are most numerous at branching points and areas of turbulence and trauma."
Entered by Uri M
ID 113056