Fraction of duplicated gene pairs that are on the same strand in fly & worm

Range ~70 %
Organism Metazoa animals
Reference Rubin GM et al., Comparative genomics of the eukaryotes. Science. 2000 Mar 24 287(5461):2204-15. p.2205 left columnPubMed ID10731134
Method Abstract: "A comparative analysis of the genomes of Drosophila melanogaster, Caenorhabditis elegans, and Saccharomyces cerevisiae-and the proteins they are predicted to encode-was undertaken in the context of cellular, developmental, and evolutionary processes."
Comments P.2205 left column: "Gene Duplications: Much of the genomes of flies and worms consists of duplicated genes [investigators] next asked how these paralogs are arranged. The frequency of local gene duplications and the number of their constituent genes differ widely between fly and worm, although in both genomes most paralogs are dispersed. The fly genome contains half the number of local gene duplications relative to C. elegans (ref 4), and these gene clusters are distributed randomly along the chromosome arms in C. elegans there is a concentration of gene duplications in the recombinogenic segments of the autosomal arms (ref 1). In both organisms, approximately 70% of duplicated gene pairs are on the same strand (306 out of 417 for D. melanogaster and 581 out of 826 for C. elegans)."
Entered by yas
ID 112750