Standard Gibbs free energy of glycolytic reactions at various pH and ionic strengths

Range Table - link kJ/mol
Organism Generic
Reference Park JO et al., Metabolite concentrations, fluxes and free energies imply efficient enzyme usage. Nat Chem Biol. 2016 May 2. doi: 10.1038/nchembio.2077. Supplementary Information pp.10-11 Supplementary Table 7PubMed ID27159581
Method Abstract: "Here [investigators] use isotope labeling to measure absolute metabolite concentrations and fluxes in Escherichia coli, yeast and a mammalian cell line. [They] then integrate this information to obtain a unified set of concentrations and ΔG for each organism."
Comments P.10 left column 2nd paragraph: "The sensitivity of ΔG°′ on pH and ionic strength and the standard error of ΔG°′ are shown in Supplementary Tables 7 and 8. The uncertainties were generally greater than the perturbations of ΔG°′ resulting from changes up to ± 0.4 pH and ± 0.1 M ionic strength, and therefore, the impact of pH and ionic strength variation within these ranges should minimally affect the subsequent integrative analysis."
Entered by Uri M
ID 112696