List of estimated protein concentrations in egg summed by assigned gene symbol

Range Excel Table - link nM
Organism African clawed frog Xenopus laevis
Reference Wühr M et al., Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database. Curr Biol. 2014 Jul 7 24(13):1467-75. doi: 10.1016/j.cub.2014.05.044. Supplementary Material Table S5PubMed ID24954049
Method Abstract: "Mass spectrometry-based proteomics enables the global identification and quantification of proteins and their posttranslational modifications in complex biological samples...Here, [investigators] demonstrate the feasibility of deep genomefree proteomics by using a reference proteome derived from heterogeneous mRNA data. [They] identify more than 11,000 proteins with 99% confidence from the unfertilized Xenopus laevis egg and estimate protein abundance with approximately 2-fold precision."
Comments P.1471 left column top paragraph: "As an additional resource, [investigators] provide the protein concentrations summed by their assigned human gene symbols (Table S5). Several distinct Xenopus proteins were mapped to the same human gene symbol. This is because similar but distinct proteins in X. laevis matched the same human gene during gene symbol assignment. The search results from the preliminary genome indicate that [they] identified nearly 10,000 distinct X. laevis genes (gene models do not contain splice variants)."
Entered by Uri M
ID 112554