Bending stiffness of membrane of ER [endoplasmic reticulum] and Golgi

Range ~3.3×10^−19 N/m
Organism Chicken Gallus gallus
Reference Upadhyaya A, Sheetz MP. Tension in tubulovesicular networks of Golgi and endoplasmic reticulum membranes. Biophys J. 2004 May86(5):2923-8. p.2926 right column bottom paragraphPubMed ID15111408
Method P.2926 right column bottom paragraph: "From the contrast of the tubules in the DIC [Differential Interference Contrast microscopy] images it was possible to estimate the relative diameters (Fig. 4)."
Comments P.2926 right column bottom paragraph: "Golgi tubules had an average diameter of ∼180 nm whereas the ER network branches were ∼115 nm in diameter [BNID 112517] or a factor of RG/RE= 1.57 ± 0.2 (Fig. 4). The inverse ratio of tether forces is FE/FG = 1.63 ± 0.3 [See values in range of BNID 112516]. [Investigators] find that the two ratios (FE/FG and RG/RE) are the same within experimental error. This implies that both membrane types have approximately the same bending stiffness: BE ≈ BG ≈ 3.3 × 10^−19 N/m, similar to that of growth cone membranes and phospholipid bilayers (Dai and Sheetz, 1995a, Evans and Rawicz, 1990 Song and Waugh, 1993)."
Entered by Uri M
ID 112518