Number of vesicles in Calyx of Held presynaptic terminal

Range electron microscopy study ≥70,000: another study ~188,000 vesicles
Organism Rat Rattus norvegicus
Reference Rizzoli SO, Betz WJ. Synaptic vesicle pools. Nat Rev Neurosci. 2005 Jan6(1):57-69. P.60 right column 2nd paragraphPubMed ID15611727
Primary Source [21] de Lange, R. P., de Roos, A. D. & Borst, J. G. Two modes of vesicle recycling in the rat calyx of Held. J. Neurosci. 23, 10164–10173 (2003) p.10166 left column 8th paragraph [50] Satzler, K. et al. Three-dimensional reconstruction of a calyx of Held and its postsynaptic principal neuron in the medial nucleus of the trapezoid body. J. Neurosci. 22, 10567–10579 (2002).PubMed ID14602833, 12486149
Comments P.60 right column 2nd paragraph: "Calyx of Held presynaptic terminal: The total number of vesicles at this synapse in the rat (Fig. 5) was estimated in a recent electron microscopy study [primary source 50] to be at least 70,000 quanta. A higher estimate — approx 188,000 vesicles — was obtained in another study [primary source 21 p.10166 left column 8th paragraph]." Primary source 21 gives value of 188,000±8000 (SEM) synaptic vesicles [SVs]
Entered by Uri M
ID 112443