| Comments |
P.143 left column top paragraph:"As shown in Figure 2A and Figure 2B, the fluorescent profile of each protein traveled down the axon anterogradely. Both moving profile showed significant effect due to diffusion, but their transporting speed was much slower than that of axoplasmic vesicles. As shown in Figure 2A and Figure 2B and Table 1, both proteins [tubulin and creatine kinase] were transported at similar speeds and time course at first. The transport speed of tubulin within 20 min after injection was 149.2 ± 43.6 μm/hr (n = 8) and that of creatine kinase was 151.7 ± 49.6 μm/hr (n = 9). But long-term (1 or 2 hr) measurement revealed that the moving speed decreased time-dependently, and the speed of creatine kinase (1 hr, 84.9 ± 11.6 μm/hr [n = 5] 2 hr, 98.2 ± 16.9 μm/hr [n = 5]), was faster than that of tubulin (1 hr, 34.2 ± 14.7 μm/hr [n = 4] 2 hr, 38.7 ± 16.9 μm/hr [n = 4]) (Table 1) the estimated transporting speed of creatine kinase at 1 or 2 hr from injection was about 2.5 times faster than that of tubulin, both of which were compatible within the range of slow axonal transport rate." Animals studied were Heterololigo bleekeri, Todarodes pacificus pacificus, or Loligo pealei. |