| Comments |
p.2676 right column bottom paragraph:"One cell system allowing such studies [of the specific interaction of mRNP
particles with their nuclear environment] is that of the Balbiani Ring (BR) mRNPs in the salivary gland cell nuclei from Chironomus tentans. These nuclei are large, and though being in interphase, their chromatin is concentrated in polytene chromosomes, which are surrounded by a vast region of chromatin-free nucleoplasm (refs 23,24). Here exists the unique situation, where mRNP mobility can be studied without the obstruction of chromatin. Several genes coding for salivary proteins are up to 40 kilobases and the size of their mRNA is only slightly reduced by splicing (ref 25). The corresponding mRNPs have a diameter of ~50 nm and contain internal repetitive sequences." For Stokes diameter of the BR2 [Balbiani Ring 2] mRNP of 36±12 nm see Siebrasse et al 2008 PMID 19074261 p.20294 right column bottom paragraph |