Number of copies of circular genome in mitochondrion

Range 1,000 - 10,000 genome copies/mitochonrion
Organism Human Homo sapiens
Reference Iborra FJ, Kimura H, Cook PR. The functional organization of mitochondrial genomes in human cells. BMC Biol. 2004 May 24 2: 9. p.1 right column bottom paragraphPubMed ID15157274
Primary Source [9] Shadel GS, Clayton DA: Mitochondrial DNA maintenance in vertebrates. Annu Rev Biochem 1997, 66: 409-435. [10] Shoubridge EA: The ABCs of mitochondrial transcription. Nat Genet 2002, 31: 227-228.PubMed ID9242913, 12089513
Comments p.1 right column bottom paragraph:"In most human cells, mitochondria contain 10^3–10^4 copies of a circular genome of 16,569 base-pairs that encodes two ribosomal RNAs, 22 tRNAs, and 13 polypeptides that form parts of the respiratory-chain located in the inner mitochondrial membrane [primary sources]."
Entered by Uri M
ID 111749