Duration of S (synthesis) phase in microarray experiment

Range ~55 min
Organism Budding yeast Saccharomyces cerevisiae
Reference Raghuraman et al., Replication dynamics of the yeast genome. Science. 2001 Oct 5 294(5540):115-21. DOI: 10.1126/science.294.5540.115 p.118 right column bottom paragraphPubMed ID11588253
Method Abstract:"Oligonucleotide microarrays were used to map the detailed topography of chromosome replication in the budding yeast Saccharomyces cerevisiae."
Comments p.118 right column bottom paragraph:"S phase in the microarray experiment spans an interval of ~55 min. Although [investigators] have previously described origins as belonging to distinct “early” or “late” classes, this genome-wide analysis reveals that origins really show a continuum of activation times (Fig. 5A). Most of the origin firings occur near mid-S."
Entered by Uri M
ID 111674