Distance between the TATA box and TSS [Transcription Start Site] for TATA box-containing genes

Range ~30 Base pairs
Organism Eukaryotes
Reference Liu X, Bushnell DA, Kornberg RD. RNA polymerase II transcription: structure and mechanism. Biochim Biophys Acta. 2013 Jan1829(1):2-8. doi: 10.1016/j.bbagrm.2012.09.003. p.4 left column bottom paragraphPubMed ID23000482
Primary Source S.T. Smale, J.T. Kadonaga, The RNA polymerase II core promoter, Annu. Rev. Biochem. 72 (2003) 449–479.PubMed ID12651739
Comments p.4 left column bottom paragraph:"The distance between the TATA box and TSS is almost always about 30 bp for TATA box-containing genes [primary source]. Consistent with this, the structural model of the minimal open promoter complex constructed from the pol II–TFIIB crystal structure defines a template strand path of approximately 30 residues from the TATA box to the catalytic site [ref 9] and [ref 10]. The notable exception is Saccharomyces cerevisiae, in which the distance from the TATA box to the TSS is 40–120 bp [BNID 111572]."
Entered by Uri M
ID 111571