| Value |
15
min
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Mackie GA RNase E: at the interface of bacterial RNA processing and decay. Nat Rev Microbiol. 2013 Jan11(1):45-57. doi: 10.1038/nrmicro2930. p.49 right column 2nd paragraphPubMed ID23241849
|
| Primary Source |
Emory, S. A., Bouvet, P. & Belasco, J. G. A. 5?-terminal stem loop structure can stabilize mRNA in Escherichia coli. Genes Dev. 6, 135–148 (1992).PubMed ID1370426
|
| Method |
Primary source abstract:"To elucidate the structural basis of differential mRNA stability in bacteria, the domains of the ompA 5'-untranslated region that allow it to protect mRNA from degradation have been identified by mutational analysis." |
| Comments |
"Thus, in E. coli, typical mRNA
half-lives (determined by northern blotting or RNase protection)
are 60–120 seconds, although a few mRNAs (for
example, ompA) display half-lives of up to 15 minutes [primary source]." |
| Entered by |
Uri M |
| ID |
111535 |