Time for amplitude of cone early receptor potential to recover after illumination (half-life)

Range 5 - 6 min
Organism Frog Rana pipiens
Reference Saari JC. Biochemistry of visual pigment regeneration: the Friedenwald lecture. Invest Ophthalmol Vis Sci. 2000 Feb41(2):337-48. p.345 left column bottom paragraphPubMed ID10670460
Primary Source [112] Goldstein EB. Early receptor potential of the isolated frog (Rana pipiens) retina. Vision Res. 1967 7: 837–845. [113] Goldstein EB. Cone pigment regeneration in the isolated frog retina. Vision Res. 1970 10:1065–1068. [114] Goldstein EB, Wolf BM. Regeneration of the green-rod pigment in the isolated frog retina. Vision Res. 1973 13: 527–534.PubMed ID5615777, 5492790, 4540349
Comments "Goldstein noted that the amplitude of the cone but not the rod early receptor potential reaches a steady state in illuminated, isolated frog retina and recovers with a t1/2 of 5 to 6 minutes in the dark.[primary sources] Thus, it appears that cones can regenerate their visual pigment in frog retina in the absence of RPE [retinal pigment epithelial]."
Entered by Uri M
ID 111400