Size of genome

Value 1.41e+9 bp Range: 26,206 protein coding genes bp
Organism Zebrafish Danio rerio
Reference Howe K et al., The zebrafish reference genome sequence and its relationship to the human genome. Nature. 2013 Apr 25 496(7446):498-503. doi: 10.1038/nature12111. p.499 table 1PubMed ID23594743
Method "[Researchers] generated a high- quality sequence assembly of the zebrafish genome, made up of an overlapping set of completely sequenced large-insert clones that were ordered and oriented using a high-resolution high-density meiotic map."
Comments p.499 left column 2nd paragraph:"The zebrafish genome-sequencing project was initiated at the Wellcome Trust Sanger Institute in 2001. [Researchers] chose Tubingen as the zebrafish reference strain as it had been used extensively to identify mutations affecting embryogenesis [ref 2]. [Their] strategy resembled the clone-by-clone sequencing approach adopted previously for both the human and mouse genome projects. The Zv9 assembly is a hybrid of high-quality finished clone sequence (83%) and whole-genome shotgun(WGS) sequence (17%), with a total size of 1.412 gigabases (Gb) (Table 1)." According to table 1 total length(bp) 1,412,464,843. p.499 left column 3rd paragraph: "Zebrafish possess 26,206 protein-coding genes [ref 6], more than any previously sequenced vertebrate, and they have a higher number of species-specific genes in their genome than do human, mouse or chicken. Some of this increased gene number is likely to be a consequence of the TSD [teleost-specific genome duplication]."
Entered by Uri M
ID 111374