| Range |
Table - link
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Naas T, Blot M, Fitch WM, Arber W. Insertion sequence-related genetic variation in resting Escherichia coli K-12. Genetics. 1994 Mar136(3):721-30. p.725 table 1PubMed ID7911771
|
| Primary Source |
Birkenbihl RP, Vielmetter W. Complete maps of IS1, IS2, IS3, IS4, IS5, IS30 and IS150 locations in Escherichia coli K12. Mol Gen Genet. 1989 Dec220(1):147-53. & Birkenbihl RP, Vielmetter W. Completion of the IS map in E. coli: IS186 positions on the E. coli K12 chromosome. Mol Gen Genet. 1991 Apr226(1-2):318-20.PubMed ID2558284, 1851952
|
| Comments |
"Genetic variation acquired
upon prolonged storage was first measured with the
copy number per subclone for each IS element (Table
1). For the eight IS probes used, the total copy number
varied from 40 to 55 among individual subclones. Considering
an average length of an IS to be about 1 kb, this
represents a 15-kb difference for the chromosome size
within the same clone of bacteria. Although this is not
a large proportion (ca. 0.3% of the chromosome
length), it indicates a fairly good amount of DNA rearrangements...Sixty eight different
patterns (57%) were found after hybridization of the
eight IS probes to the DNA of 118 individuals (Table 1).
Fifty one different patterns were represented by one
unique individual subclone in the sample surveyed indicating
that the polymorphism arose under almost non-replicating
conditions. Based on the parsimony method,
a pedigree was designed (Figure 3) which required at
least 174 mutational steps to explain the observed distribution
of patterns." See notes beneath table |
| Entered by |
Uri M |
| ID |
111311 |