| Value |
8.9E-11
mutation/basepair/generation
Range: 4.0E-11 - 14E-11 Table - link mutation/basepair/generation
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Wielgoss S. et al., Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli. G3 (Bethesda). 2011 Aug 1 1(3):183-186. p.185 table 2 & right column top paragraphPubMed ID22207905
|
| Comments |
"[Researchers] observed a total of 52 synonymous substitutions in the 19
resequenced genomes (Table S1). However, multiple genomes sampled
from the same population are not independent because they
share some portion of their history thus, there were only 35 mutational
events (Table 1). [They] used a resampling procedure to account
for this pseudo-replication of multiple genomes isolated from a single
population (see supporting information). The resulting estimate of the
point-mutation rate is 8.9×10^-11 per bp per generation (Tukey’s
jackknife 95% confidence interval, 4.0–14×10^-11 per bp per generation).
This estimate corresponds to a total genomic rate of 0.00041
per generation given the ancestral genome size of 4.6×10^6 bp." See notes beneath table |
| Entered by |
Uri M |
| ID |
111230 |