Flux of proteins entering the endoplasmic reticulum (ER) lumen

Value 460 molecules/second Range: 78-3700 molecules/second molecules/second
Organism Budding yeast Saccharomyces cerevisiae
Reference Vincent, M., Whidden, M., & Schnell, S. (2014). Surveying the floodgates: estimating protein flux into the endoplasmic reticulum lumen in Saccharomyces cerevisiae. Frontiers in Physiology, 5, 444. doi:10.3389/fphys.2014.00444 abstractPubMed ID25431559
Method Abstract: "In this work [investigators] carried out a meta-analysis to estimate the average and absolute flux of proteins into the endoplasmic reticulum lumen." Theoretical estimate. See reference for details.
Comments Abstract: "[Investigators] estimate an average of 460 proteins enter the endoplasmic reticulum every second, with an absolute minimum and maximum flux of 78 and 3700 molecules per second, respectively."
Entered by mvincent
ID 111187