Fraction of genes that are in the leading strand

Range Firmicutes (including mycoplasmas) 78%: other bacterial genomes 58% %
Organism bacteria
Reference Rocha EP. The replication-related organization of bacterial genomes. Microbiology. 2004 Jun150(Pt 6):1609-27. p.1613 left column top paragraphPubMed ID15184548
Primary Source Rocha, E. P. C. (2002). Is there a role for replication fork asymmetry in the distribution of genes in bacterial genomes? Trends Microbiol 10 , 393–396.PubMed ID12217498
Comments "A first systematic survey of gene strand bias showed that genomes could have from 55 to 80% of genes in the leading strand, although systematically more than 85 % of ribosomal proteins were coded in the leading strand of these genomes (McLean et al., 1998). In fact, 78 % of the genes of Firmicutes (including mycoplasmas) are in the leading strand, compared with 58 % for the other genomes (primary source)."
Entered by Uri M
ID 110940