Thickness of lamellipodium in keratocytes

Range 140 - 200 nm
Organism Fish Black tetra Gymnocorymbus ternetzi
Reference Laurent VM et al., Gradient of rigidity in the lamellipodia of migrating cells revealed by atomic force microscopy. Biophys J. 2005 Jul89(1):667-75. p.673 left column 2nd paragraphPubMed ID15849253
Method Selected ion monitoring (SIM) & Atomic Force Microscopy (AFM)
Comments "[Researchers] estimated the elastic modulus of the front edge of the keratocyte lamellipodium at 10–55 kPa. It is necessary to note that these values represent only apparent stiffness, because the lamellipodium is very thin (140–200 nm) and the indentation by the AFM [Atomic Force Microscopy] probe in [researchers'] experiments was significant with respect to thickness of the lamellipodia."
Entered by Uri M
ID 110904