Actin assembly at the lamellipodial margin

Range Table - link
Organism Mammalian tissue culture cell
Reference Abraham VC, Krishnamurthi V, Taylor DL, Lanni F. The actin-based nanomachine at the leading edge of migrating cells. Biophys J. 1999 Sep77(3):1721-32 p.1728 table 2PubMed ID10465781
Primary Source See pointers to refs and refs beneath table
Comments "[Researchers'] data on lamellipodial thickness and F-actin density in fibroblasts can be combined with previous studies on actin dynamics to quantify several important features of actin assembly at the leading edge (Table 2). These include 1) the density of assembling filament ends at the lamellipodial margin, 2) the volume density of F-actin, 3) the minimum concentration gradient of unassembled actin at the margin required to support assembly, and 4) the maximum force and pressure that actin assembly could generate at the leading edge. The following sections discuss the important points with regard to the calculations summarized in Table 2."
Entered by Uri M
ID 110741