Range |
Table - link % of glucose-derived carbon in biomass
|
Organism |
Human Homo sapiens |
Reference |
Chen YJ, Huang X, Mahieu NG, Cho K, Schaefer J, Patti GJ. Differential Incorporation of Glucose into Biomass during Warburg Metabolism. Biochemistry. 2014 Jul 29 53(29):4755-7. doi: 10.1021/bi500763u. p.4756 table 1PubMed ID25010499
|
Method |
"[Researchers'] approach to studying the fate of glucose was to integrate
two complementary metabolomic technologies: solid-state
nuclear magnetic resonance (NMR) and liquid chromatography/mass spectrometry (LC/MS)." |
Comments |
"By monitoring changes in the integrated intensity of the 13C3 peak
of lactate (22 ppm), [researchers] determined that 76% of labeled glucose
carbon is secreted as lactate. The combination of multiple
NMR experiments allowed the quantitation of the fate of
labeled glucose carbon in proteins, peptides, intracellular sugars
and glycerol, and lipids, yielding values of 9, 2, 7, and 4%,
respectively (Table 1)." |
Entered by |
Uri M |
ID |
110719 |