Fraction of viral forms (in gut virome) that persisted over the 2.5-y time course studied

Range ~80 %
Organism Human Homo sapiens
Reference Minot S, Bryson A, Chehoud C, Wu GD, Lewis JD, Bushman FD. Rapid evolution of the human gut virome. Proc Natl Acad Sci U S A. 2013 Jul 23 110(30):12450-5. doi: 10.1073/pnas.1300833110. p.12454 right column 2nd paragraphPubMed ID23836644
Primary Source [4] Reyes A, et al. (2010) Viruses in the faecal microbiota of monozygotic twins and their mothers. Nature 466(7304):334–338. [5] Minot S, et al. (2011) The human gut virome: inter-individual variation and dynamic response to diet. Genome Res 21(10):1616–1625. [6] Minot S, Grunberg S, Wu GD, Lewis JD, Bushman FD (2012) Hypervariable loci in the human gut virome. Proc Natl Acad Sci USA 109(10):3962–3966.)PubMed ID20631792, 21880779, 22355105
Method "To investigate the origin and nature of human viral populations, [researchers] carried out a detailed study of a single human gut viral community. Ultra-deep longitudinal analysis of DNA sequences from the viral community, combined with characterization of the host bacteria, revealed rapid change over time and begins to specify some of the mechanisms involved."
Comments "[Researchers] report a study of longitudinal variation in the human gut virome and some of the mechanisms responsible for change over time. Loss and acquisition of viral types was uncommon: Fully ~80% of viral forms persisted over the 2.5-y time course studied, as is consistent with previous studies of shorter duration (primary sources)."
Entered by Uri M
ID 110710