Number of epithelial cells in small intestine that are produced and discarded during lifetime

Range ~1E+13 cells
Organism Rat Rattus norvegicus
Reference Cairns J. 1975. Mutation selection and the natural history of cancer. Nature 255: 197–200. p.197 left column 2nd paragraphPubMed ID1143315
Primary Source Enesco & Leblond, Increase in Cell Number as a Factor in the Growth of the Organs and Tissues of the Young Male Rat, Embryol. exp. morph. 10, 530-562 (1962)
Comments "During its entire lifetime, however, the rat produces and discards about 10^13 epithelial cells from its small intestine alone, and almost as many cells from various other epithelia (primary source). Its risk of being overwhelmed by variants, is, in principle at least, related to this total of 10^13."
Entered by Uri M
ID 110650