ATP maintenance cost as used in the common FBA COBRA framework

Value 8.4 mmol ATP/gCDW/h
Organism Bacteria Escherichia coli
Reference What is flux balance analysis? Jeffrey D Orth, Ines Thiele & Bernhard Ø Palsson, Nature Biotechnology 28, 245–248 (2010) doi:10.1038/nbt.1614. in the SI pp. 4
Method "Because the maximum amount of ATP that can be produced from this amount of succinate is less than the minimum bound of 8.39 mmol gDW-1 hr-1 of the ATP maintenance reaction, ATPM, there is no feasible solution."
Comments There is no primary ref given for the value chosen for the simulation tool
Entered by Ron Milo - Admin
ID 110630