| Range |
650 - 800 kDa
|
| Organism |
Fungus Tolypocladium inflatum (Beauveria nivea) |
| Reference |
Lawen A, Zocher R. Cyclosporin synthetase. The most complex peptide synthesizing multienzyme polypeptide so far described. J Biol Chem. 1990 Jul 5 265(19):11355-60. p.11360 left column 2nd paragraphPubMed ID2358465
|
| Method |
"Measurements of the molecular
weight of the native cyclosporin synthetase were performed
by ultracentrifugation in glycerol gradients along with
standard proteins." |
| Comments |
"The molecular mass of cyclosporin synthetase has been
determined to be between 650 and 800 kDa. In spite of this
high value, [researchers] were not able to dissociate the enzyme into
subunits neither with urea nor with detergents like SDS nor
with ß-mercaptoethanol." |
| Entered by |
Uri M |
| ID |
110414 |