Plasma cell antibody secretion rate

Range 50 - 340 pg Ig/cell/day
Organism Human Homo sapiens
Reference Bromage E, Stephens R, Hassoun L. The third dimension of ELISPOTs: quantifying antibody secretion from individual plasma cells. J Immunol Methods. 2009 Jul 31 346(1-2):75-9. doi: 10.1016/j.jim.2009.05.005. p.78 right column top paragraphPubMed ID19465022
Primary Source Salmon, S.E., Smith, B.A., 1970. Immunoglobulin synthesis and total body tumor cell number in IgG multiple myeloma. J. Clin. Invest. 49, 1114.PubMed ID4987170
Method "To determine antibody secretion rates within an individual, Salmon and Smith estimated total number of antibody secreting cells and production of antibody in vivo to calculate that plasma cells were secreting between 50 and 340 pg Ig/cell/day (primary source)."
Entered by Uri M
ID 110221