Mean DNA replication rate

Value 2.8 kb/min Range: ±1.0 kb/min
Organism Budding yeast Saccharomyces cerevisiae
Reference Sekedat MD, Fenyö D, Rogers RS, Tackett AJ, Aitchison JD, Chait BT. GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Mol Syst Biol. 2010 6: 353. doi: 10.1038/msb.2010.8 p.2 left column 3rd paragraphPubMed ID20212525
Primary Source Yabuki N, Terashima H, Kitada K (2002) Mapping of early firing origins on a replication profile of budding yeast. Genes Cells 7: 781–789PubMed ID12167157
Method "A microarray technology was applied to obtain a genome-wide profile of DNA replication and to classify early firing origins."
Comments "A wide range of nucleotide incorporation rates (0.5–11 kb/min) were observed, with a mean of 2.9 kb/min (BNID 110149), whereas a second study reported a comparable mean rate of DNA duplication of 2.8±1.0 kb/min (primary source)."
Entered by Uri M
ID 110150